CELSB Past Seminars
2008 Jesse Frumkin, PhD Student 25-Apr 4-5pm Building 517, Room 147 Nathaniel Freund, PhD Student 16-Apr 4-5pm Building 517, Room 147 Eric Tan, PhD Student 14-Mar 4-5pm Building 517, Room 147 "Thermodynamic Prediction of Protein Neutrality" Dimitris Iliopoulos February 27, 2008 1:00-2:00pm "Rapid Motion in the Planet Kingdom: A Biomechanical Study of the Venus Flytrap" Maged Ismail February 20, 2008 1:00-2:00pm "Backwards and forwards: induced pleuripotent stem cells" Ian Phillips January 18, 2008 4:00-5:00pm 2007 Jiefeng Qian "Mining Complex Genotypic Features for Predicting HIV-1 Drug Resistance" December 14, 2007 4:00-5:00pm Sri Ramakrishana Paladugu, PhD student "Molecular Basis for Evolving Modularity in the Yeast Protein Interaction Network" December 7, 2007 4:00-5:00 PM Building 517, Room 147 Dimitris Iliopoulos, PhD student December 5, 2007 1:00-2:00 PM Building 535, Room 152/154 Nicolas Chaumont, PhD student "Qualitative Differential Equations: Bridging the gap between over-fitted mathematical models and non-quantitative experimental data" November 30, 2007 4:00-5:00 PM Building 517, Room 147 Abstract: Many biological phenomena should reduce to differential equations. However, when one finds that a model is wrong, it is difficult to distinguish between several sources of error: (1) parameters; (2) the form of one or more of the equations; (3) the qualitative assumptions made. To biologists and mathematicians alike, the most important errors are qualitative: Has one left out essential chemicals? Are there unknown physical interactions? Are some activators really inhibitors? In this journal club, I present Benjamin Kuiper's method for (1) rapidly disproving the qualitative assumptions of a model; (2) Rapidly identifying new experiments that might definitively disprove the qualitative assumptions of a model; (3) rapidly modifying models; and (4) rapidly constructing new models. Uniquely, the method does not require quantitative measurements by biologists, but instead works with qualitative phenotypes and genetic interactions that make up mainstream biology. Nathaniel Freund "Self-crosslinked gliadin fibers with high strength and water stability for potential medical applications" November 28, 2007 1:00-2:00pm Bjorn Ostman "Bacterial Adaptive Radiation" November 16, 2007 4:00-5:00pm Jesse Frumkin, PhD student October 17, 2007 4:00-5:00 PM Building 517, Room 147 Dimitris Iliopoulos, PhD student "Is HIV-1 becoming attenuated or more mutationally robust?" October 12, 2007 4:00-5:00 PM Building 517, Room 147
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